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Phase I clinical trial of RO7589831 in participants with advanced solid tumors.

THE MAIN OBJECTIVE OF THIS TRIAL IS TO TEST WHETHER RO7589831 ADMINISTERED AT DIFFERENT DOSES HAS EFFECTS (GOOD OR BAD), AS WELL AS WHAT HAPPENS TO RO7589831 ONCE IT HAS ENTERED THE BODY AND HOW IT ACTS ON THE BODY AND ITS DISEASE.

Status
In recruitment
headquarters
Pamplona/Madrid
Early phase

Technical Summary

  • PHASE I OPEN-LABEL STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND ANTITUMOR ACTIVITY OF RO7589831 IN PARTICIPANTS WITH ADVANCED SOLID TUMORS CARRYING MICROSATELLITE INSTABILITY (MSII) AND/OR DEFICIENCY IN MISMATCH REPAIR (DMMR) SYSTEM
  • Code EudraCT: 2023-503170-20-00
  • Protocol number: BP44474
  • Promoter: Roche Farma, S.A.
  • Molecule/Drug: RO7589831

* The trials only admit a limited number of patients and are subject to inclusion and exclusion criteria. The specialist who assesses your case will inform you of the conditions required to participate in the clinical trial.

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