Scientific publications
Druggable targets in cytokine release syndromes. Scientific Publication
Sep 1, 2023
| Magazine: Clinical Cancer Research
Carlos Luri-Rey 1 , Iñaki Eguren-Santamaria 2 , Ignacio Matos 3 , Pedro Berraondo 4 , Ignacio Melero 5
Abstract
Bispecific T-cell engagers and CAR T-cells share the problem of eliciting acute systemic inflammation episodes known as Cytokine Release Syndrome (CRS).
Knowledge on the sequential waves of cytokines that can be neutralized with clinically available agents is crucial to prevent or treat this condition without jeopardizing the antitumor therapeutic outcome.
CITATION Clin Cancer Res. 2023 Sep 1. doi: 10.1158/1078-0432.CCR-23-1975
Our authors
Specialist
Medical Oncology Department
Navarre headquarters
Codirector
Immunology and Immunotherapy Department
Navarre headquarters