Scientific publications

Management of cytomegalovirus in adult solid organ transplant patients: GESITRA-IC-SEIMC, CIBERINFEC, and SET recommendations update. Scientific Publication

Aug 5, 2024 | Magazine: Transplantation Review

Elisa Ruiz-Arabi  1 , Julian Torre-Cisneros  2 , Victoria Aguilera  3 , Rodrigo Alonso  4 , Marina Berenguer  3 , Oriol Bestard  5 , Marta Bodro  6 , Sara Cantisán  7 , Jordi Carratalà  8 , Juan José Castón  7 , Elisa Cordero  9 , Carme Facundo  10 , María Carmen Fariñas  11 , Mirian Fernández-Alonso  12 , Mario Fernández-Ruiz  13 , Jesús Fortún  14 , Maria Dolores García-Cosío  15 , Sabina Herrera  16 , David Iturbe-Fernández  17 , Oscar Len  18 , Francisco López-Medrano  13 , María Ovidia López-Oliva  19 , Ibai Los-Arcos  20 , María Ángeles Marcos  21 , Pilar Martín-Dávila  14 , Víctor Monforte  22 , Patricia Muñoz  23 , David Navarro  24 , Aurora Páez-Vega  25 , Ana Belén Pérez  26 , Natalia Redondo  13 , Regino Rodríguez Álvarez  27 , Alberto Rodríguez-Benot  28 , Isabel Rodríguez-Goncer  13 , Rafael San-Juan  13 , Javier Sánchez-Céspedes  29 , Maricela Valerio  23 , José Manuel Vaquero  30 , Diego Viasus  31 , Elisa Vidal  7 , José María Aguado  32


Abstract

Cytomegalovirus (CMV) infection remains a significant challenge in solid organ transplantation (SOT). The last international consensus guidelines on the management of CMV in SOT were published in 2018, highlighting the need for revision to incorporate recent advances, notably in cell-mediated immunity monitoring, which could alter the current standard of care.

A working group including members from the Group for the Study of Infection in Transplantation and the Immunocompromised Host (GESITRA-IC) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Society of Transplantation (SET), developed consensus-based recommendations for managing CMV infection in SOT recipients.

Recommendations were classified based on evidence strength and quality using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The final recommendations were endorsed through a consensus meeting and approved by the expert panel.

CITATION  Transplant Rev (Orlando). 2024 Aug 5;38(4):100875. doi: 10.1016/j.trre.2024.100875