Scientific publications
Takotsubo cardiomyopathy secondary to electroconvulsive therapy in a young adult with Down syndrome regression disorder. Scientific Publication
María Del Carmen Ortega 1 , José Pablo Bullard 2 , María Del Mar Unceta 2 , Felipe Ortuño Sánchez-Pedreño 2 3 , Patricio Molero 2 3 , Diego Real de Asúa 4
Abstract
We report the case of an 18-year-old woman with Down syndrome (DS) who developed Takotsubo cardiomyopathy (TSC) immediately after the administration of electroconvulsive therapy (ECT), a treatment prescribed for Down syndrome regression disorder resistant to oral psychotropic drugs.
TSC is a nonischemic cardiomyopathy related to psychological or physical stress, which has been described as a rare complication of ECT (Kinoshita et al., 2023, Journal of Electroconvulsive Therapy, 39, 185-192).
The clinical description of the case is accompanied by a discussion of the peculiarities of the autonomic nervous system in DS.
CITATION Am J Med Genet C Semin Med Genet . 2023 Dec 1:e32078. doi: 10.1002/ajmg.c.32078
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