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Clinical trial to evaluate the safety, tolerability and pharmacokinetics of the anti-CCR8 antibody BAY 3375968, in monotherapy and in combination with pembrolizumab, in patients with selected advanced solid tumors.

THE MAIN OBJECTIVE IS TO LEARN WHETHER BAY 3375968 ADMINISTERED ALONE OR IN COMBINATION WITH PEMBROLIZUMAB IS SAFE FOR PARTICIPANTS AND HOW IT AFFECTS THE BODY.

Status
In recruitment
headquarters
Pamplona/Madrid
Early phase

Technical Summary

  • FIRST-IN-HUMAN, DOSE-ESCALATING, EXTENDED DOSE ESCALATION TRIAL TO EVALUATE THE SAFETY, TOLERABILITY AND PHARMACOKINETICS OF THE ANTI-CCR8 ANTIBODY BAY 3375968, IN MONOTHERAPY AND IN COMBINATION WITH PEMBROLIZUMAB, IN PATIENTS WITH SELECTED ADVANCED SOLID TUMORS
  • Code EudraCT: 2023-505594-32-00
  • Protocol number: 21820 /BAY3375968
  • Promoter: Bayer Hispania S.L
  • Molecule/Drug: BAY3375968

* The trials only admit a limited number of patients and are subject to inclusion and exclusion criteria. The specialist who assesses your case will inform you of the conditions required to participate in the clinical trial.

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