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Phase I/II clinical trial of the selective PARP1 inhibitor, IMP1734, in participants with advanced solid tumors.
THE MAIN OBJECTIVE OF THIS STUDY IS TO EVALUATE THE EXTENT TO WHICH IMP1734 IS TOLERATED, ALONE AND IN COMBINATION WITH OTHER ANTICANCER DRUGS, AS A TREATMENT FOR PATIENTS WITH OVARIAN, BREAST, PROSTATE AND PANCREATIC CANCER.
Technical Summary
- FIRST HUMAN, PHASE I/II, UNBLINDED, MULTICENTER, MULTICENTER, STEPWISE DOSE ESCALATION, DOSE OPTIMIZATION AND DOSE ESCALATION STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS AND ANTITUMOR ACTIVITY OF THE SELECTIVE PARP1 INHIBITOR, "IMP1734", IN PATIENTS WITH ADVANCED SOLID TUMORS.
- Code EudraCT: 2023-509230-19
- Protocol number: EIK1003-001
- Promoter: Eikon Therapeutics
- Molecule/Drug: IMP1734
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