Publicaciones científicas
SEOM-GEICO Clinical Guidelines on cervical cancer (2023)
Luis Manso 1 , Avinash Ramchandani-Vaswani 2 , Ignacio Romero 3 , Luisa Sánchez-Lorenzo 4 , María José Bermejo-Pérez 5 , Purificación Estévez-García 6 , Lorena Fariña-Madrid 7 , Yolanda García García 8 , Marta Gil-Martin 9 , María Quindós 10
Abstract
Cervical cancer (CC) is the fourth most common cancer and the fourth leading cause of mortality in women worldwide. It is strongly associated with high-risk human papillomavirus infection.
High-income countries that have implemented human papillomavirus (HPV) vaccination and screening programs have seen dramatic reductions in CC incidence, while developing countries where these programs are not available continue to experience high rates of CC deaths.
In early-stage CC, the primary treatment is surgery or radiotherapy, whereas concurrent chemo-radiotherapy (CRT) remains the conventional approach in locally advanced stages until the upcoming approval of immunotherapy. The incorporation of immunotherapy in combination with chemotherapy (with or without bevacizumab) in first line and as monotherapy in second line after platinum-based chemotherapy, has significantly increased overall survival (OS) in recurrent or metastatic CC.
The purpose of this guideline is to summarize the most relevant evidence in the diagnosis, treatment, and follow-up of CC and to provide evidence-based recommendations for clinical practice.
CITA DEL ARTÍCULO Clin Transl Oncol. 2024 Nov;26(11):2771-2782. doi: 10.1007/s12094-024-03604-3. Epub 2024 Aug 31
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