Publicaciones científicas

Textbook outcome in patients with biliary duct injury during cholecystectomy

21-feb-2024 | Revista: Journal of Gastrointestinal Surgery

Victor Lopez-Lopez  1 , Christoph Kuemmerli  2 , Javier Maupoey  3 , Rafael López-Andujar  3 , Laura Lladó  4 , Kristel Mils  4 , Philip Müller  5 , Andres Valdivieso  6 , Marina Garcés-Albir  7 , Luis Sabater  7 , Andrea Benedetti Cacciaguerra  8 , Marco Vivarelli  8 , Luis Díez Valladares  9 , Sergio Annese Pérez  10 , Benito Flores  10 , Roberto Brusadin  11 , Asunción López Conesa  11 , Sagrario Martinez Cortijo  12 , Sandra Paterna  13 , Alejando Serrablo  13 , Ferdinand Heinz Walther Toop  14 , Karl Oldhafer  14 , Santiago Sánchez-Cabús  15 , Antonio González Gil  16 , Jose Antonio González Masía  17 , Carmelo Loinaz  18 , Jose Luis Lucena  19 , Patricia Pastor  20 , Cristina Garcia-Zamora  21 , Alicia Calero  22 , Juan Valiente  23 , Antonio Minguillon  24 , Fernando Rotellar  25 , Cándido Alcazar  26 , Javier Aguilo  27 , Jose Cutillas  28 , Jose A Ruiperez-Valiente  29 , Pablo Ramírez  11 , Henrik Petrowsky  30 , Jose Manuel Ramia  26 , Ricardo Robles-Campos  11


Background: Iatrogenic bile duct injury (BDI) during cholecystectomy is associated with a complex and heterogeneous management owing to the burden of morbidity until their definitive treatment. This study aimed to define the textbook outcomes (TOs) after BDI with the purpose to indicate the ideal treatment and to improve it management.

Methods: We collected data from patients with an BDI between 1990 and 2022 from 27 hospitals. TO was defined as a successful conservative treatment of the iatrogenic BDI or only minor complications after BDI or patients in whom the first repair resolves the iatrogenic BDI without complications or with minor complications.

Results: We included 808 patients and a total of 394 patients (46.9%) achieved TO. Overall complications in TO and non-TO groups were 11.9% and 86%, respectively (P < .001). Major complications and mortality in the non-TO group were 57.4% and 9.2%, respectively. The use of end-to-end bile duct anastomosis repair was higher in the non-TO group (23.1 vs 7.8, P < .001). Factors associated with achieving a TO were injury in a specialized center (adjusted odds ratio [aOR], 4.01; 95% CI, 2.68-5.99; P < .001), transfer for a first repair (aOR, 5.72; 95% CI, 3.51-9.34; P < .001), conservative management (aOR, 5.00; 95% CI, 1.63-15.36; P = .005), or surgical management (aOR, 2.45; 95% CI, 1.50-4.00; P < .001).

Conclusion: TO largely depends on where the BDI is managed and the type of injury. It allows hepatobiliary centers to identify domains of improvement of perioperative management of patients with BDI.

CITA DEL ARTÍCULO  J Gastrointest Surg. 2024 Feb 21:S1091-255X(24)00334-2.  doi: 10.1016/j.gassur.2024.02.027